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Research finding
Lingzhi water extract reduced memory impairment caused by high-altitude hypoxia (rat study)
In an environment simulating high-altitude low oxygen, rats given a lingzhi water did better on spatial memory tests than rats that were not, with less nerve cell damage in the and restored levels of .
Animal studyObserved in animalsHow the study was done
Rats lived for 7 days in an environment simulating high-altitude hypoxia while receiving lingzhi water extract; spatial memory was tested in a water maze, and neurotransmitters, oxidative stress markers and memory-related proteins in the hippocampus were measured; supplementary experiments were also done on hippocampal nerve cells.
What the researchers say
The researchers believe lingzhi water extract may help maintain memory through memory-related signaling pathways and help the body adapt to low oxygen, and could potentially be used to prevent cognitive decline caused by high-altitude environments.
Source
Sharma P et al., Scientific Reports, 2020
Abstract checked Last updated: 2026-10-15